Using gene therapy, scientists have discovered that managing the level of the protein GDNF is key to the the correct transmission of dopamine, the feel-good neurotransmitter, in the brain. GDNF levels plummet when alcoholics abstain from drinking, leading to a dopamine shortage and feeling of discomfort, which makes alcoholics resort to drinking. Gene therapy is now thought to 'fix' GDNF levels, which could be a solution for those suffering from alcoholism.
